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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '34331743128c39761de8a2012c4797b41ecf17a368f4b210b4acc949ae1f33bc' 
  AND token = 'NGQmCcuFuO57RzRZxo/Hsg9Gd9A4HRjiN+cna4REwa0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}