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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd3a998cad3bdaf542c8ac12e4e16bbd13b5f55a9797890ad55ba12554f78a644' 
  AND token = 'lE/21X+UG1q+LAz02cf+ACQoCu1b62I7bT7VfKrbPCw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}