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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '78f95cbd138236f0c0db99dbf6930abed7ade430e69b7b777151766af75b6cc5' 
  AND token = 'KMgjbWnk28FvtuvOODj8qkKMAgO0OxZOTfrAbb9hcGI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}