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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3850a2925fde7cf7b6d8aa65ba2a898dd36718f302b2561c694d507cee19ee52' 
  AND token = 'IhLjTeDAE89Qv2ov9o3XZDKW148RSzMJ5wyWmdWl/Aw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}