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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'fe74c557e6dab4b13f13c5a0b04486f444fd58c66b1f901f591af6e8c211fd43' 
  AND token = 'uXi+ZVV3cf7OSgYffWkzh0qjsAfTuz8svNTQgry/t4A=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}