SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '45a146f53621bd0d58fc28e44548fd2fec37a35ec3fe1579db1b44bd906ceb72' 
  AND token = 'StWnCERhtATfOOKzwwaNB+t6vNJFzTlYX9+ohwtpl6g=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00043

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}