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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '452d976589e9d9944538647783d9702e09477b32954bcb38b541f21de0760b5d' 
  AND token = '1AroM/aP7jG8XRJQYYnGmnJr+IebAXl8vA4b0A5ByAE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00032

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}