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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4410f90b893a33b2a8f3a5af0faead35ae9a929b3f19fd4af887105d75e63d48' 
  AND token = 't9uKnR3V6/O4ZsPzON4s27fUMu1FC3nhsYHeXUrR+Z0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00015

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}