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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '462bc363fd5bceed3436169be32c1b4b10bf943b87da48f9c7b95f1d7978eacf' 
  AND token = 'M52XrR0WX0cxSlgAWlclVGtXOAG0lWieqLwr4vFo/7k=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}