SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f8865084f4fc8a4381e11fd4886bc597d9292923366503893bad8555b6bea289' 
  AND token = 'Z0VsvdIjBwjPt5SJase2d3yo5V+Bo1xzF67gyTk2NUM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}