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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a3d705482b3f938cc1e8d370ef333985ceb099306bc9fabaf9ee4ad0f1431308' 
  AND token = 'joTRBbu1JN+JDrK9Yt4D/owJ2f42RKkqXRcMRMKcH+Q=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}