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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1ced1b284952f761aaba29d319bdb6e0d118dc80dc054a4c0e7122cc4e8e5048' 
  AND token = 'JUWXwuVP4uVwdOkFKTL05Hwj8ZrK8cSKsxs+JrBxe+o=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}