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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ef9d233d556b8cf950dd4255cb3719920b05eb58feaa6c8ea703c33d454b81f5' 
  AND token = 'TJZ67tR1No1akaAvMtFSu6WkYDqTm/U7ZJW6vzV6REY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}