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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3eec1c714bac4b26b63a06c7ad7c474ba22394c2eef43682cf3429de7f3a3b89' 
  AND token = '/mPUJgLNA+5l9EyCfRrv07VCyV4BB9CqSrvM8U+dsaQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}