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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '664dd322206776bb81e41eb8a36389cf3e32f8a28e0ee9b2369f68cb4b8e7dc3' 
  AND token = 'N++EjQ3y7Gc0T6pHVDTQ1cKHxz01HHvDmSwNHk6Wnpk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}