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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8ff840ae033ecb5c9c3792ecbf8d605f2143b0bb001637625fac36cbe7354784' 
  AND token = 'k4rU8Zqlx6IDd+GjaD1n9U0pj+yMrOEsn04q4D+qbDA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}