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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '744e3335128cd786c16d41701cbf6cbd100bf64399d142f7bb4ad5903b7a78e1' 
  AND token = 'zmmj7/K3Z4hbSb+Z24tH3OYMe1dC2l0aYG2hQaFM6q8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00065

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}