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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '654172c58e24ea542cd620523f4736644e0731ba313bf73ca5719fab1df7a163' 
  AND token = 'ujYO+gDLAtOByTM9s9YDIsZxwd9o6Hsf2Kd5ffK7XWk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}