SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a35b7a5f5db5683bd09991ed0071ad9efdfe748ffcdaeb7607754bfc6829fb86' 
  AND token = 'TPeLZaHFaXNM8i3iAZdSo4V04+uQQ3QwfwT8VM9G9qo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00040

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}