SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'dfe33f52085995f031a933c493bc5e959f6231e30c7f56f002ed3c7294b10cfe' 
  AND token = 'eKeoBCMkWLjXm5uHr3vlCJoa8nYMuCWJYs99l+E7Gmc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}