SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ee08e6ba1312d3ae83f03a7d4c1f732728d188de39f928ef5921478009d428f8' 
  AND token = 'TQHi+zbV9Yiiuk8mhY1Gx8RJR2Fjhpq/8qvd6tWSjTE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}