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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '053871e928a7176050f2d7611224068c76f004992b8e1f3790eea89f5dff01df' 
  AND token = 'NNDQCvyg/0x7Rep3vZ1H6oXXKjSR3r+cCP+w3raDPEs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}