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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'acb060d1b72e6a4ed5093a543f43a30e12b0a3228f1e9c8e6f2162efcdf34e3a' 
  AND token = 'kPQ86EKTlQRGDj9whWYaITxISt9rPgUQgx7/KguX+Rc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}