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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'db2374d3d05743e93396b355c5496d35a11d26cf236bf54a35fbb7dbcb5e0d1e' 
  AND token = '3Pj1BTdwawLeRFUpXkFN1Lv09C4BEDlX7HPbvRiKg3I=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}