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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1c5b8b8fc0365ace27c9467ca3e4395225a4ca1c15c6940e0cf42125a7d38a33' 
  AND token = 'zto2s13csiBzGJeJxZ4ZUi9rCM+dom8jjEb/KEe/Wbs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}