SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '14ab2d870dc34f3916a36a045cb9a82a5cd84fb55a7c9ea6cb0b3d52273a496a' 
  AND token = 'FrLAEXlZMV7j013x13K5jk9HCKoqiw3qy3AZJ+NwmE8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00016

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}