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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f3249835fade57bde9b2ae29068fd10e9d7ef0a7cd708b70be3eb86c2419ebd2' 
  AND token = '6IgE/AUVsc9DB6NAUnPdxzIgiyS2UIM0oZQIoSICt1o=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}