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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a65f2196df82c1137f84251412edd4e6ed344c53452bc4dbf3ffa726854e6275' 
  AND token = 'kXg0P139ltuAYtQdaUbw/xQyuu3MaGGideJQ6afjPSU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}