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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2500def5f4af765619dc96d4fcf0b3015e78f208c573a0fea269174f28f5e192' 
  AND token = 'JPnBPLD1T7pwJnC0C9c1ySo8NbA1Rit653om7b0Ti6M=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}