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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '545fe4f21e6cab029da70023c5c7e37268b945cf6762c1b5a8c0b7e62f822ad9' 
  AND token = 'V4NvXJYjgHdYhaaz1bFkuYAFpNeckKQyCOI3j+V4+kM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00012

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}