SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '96d561026a93c28d4e95c0c4b0b3c8435b918cadecc71e6ce21d0bc3f2c03af8' 
  AND token = 'i5RaO2ALoTH41NDB/szyWlzzU3hA4wEM76Am+X0Rj2U=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}