SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '82d09ed391ecb68dd73aaa9d30cac51e1b83af4ee414f51efa8531e0a6d87e60' 
  AND token = 'Y5Bi0Eecd5j8T63FUfPP3dk7aGNGOJERRZeTOAwbMc0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}