SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3dcca4f805e26de2a4066257ef302a66ed4a2f59877048ff849be4041e0f7cee' 
  AND token = 'P3xhLtQ6xzO8uhYMr+mXic92gzLVkX+uZDQd9KRxFqM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}