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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'cbf99e6a222242e009ccb5e8ca3969477fb647ea1331f70521c50577482d0508' 
  AND token = 'deG8SS2lLbfBTfSVO/cWdaoozB6RqQw4+COAZnOQtrw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00041

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}