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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'aa8e0459b50472b3bc2331a0b8b93f53f0940fe6e614fec4f61dd73bcacf6dcf' 
  AND token = '4Ud6z9hXdXhSJOCnP5XoyJa021T/S1k5UGHz7BzG5Zc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}