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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0f49ef9b981e98b1b66547d91d3b4ddde7e49f2dbbe414687b962318fccbb411' 
  AND token = 'N8MIiMDYXDQSmFEZj+Z2Uz8GInPa8b1Yp3Hyirv0/ss=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}