SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3eee3721a810d43b8d9373b9df61370835a6afdd31d15e6f63a6be30d69360c6' 
  AND token = 'IJBN0ClPcbiU1Af66acXXKQpaaN9nFfh7+kEfQn+LdA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}