SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5de6d221336cc8ce32ed2a1aa7ab9eebf659b526a64973df17d54df0a968f93f' 
  AND token = 'IXuaDLziCbDAwK45ctPAE3xvPYAl3l+DUNmLwBAFsI0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}