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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'cb25df2148b8d19a98cd3166ee3e38da9653e2cc6b19f71b17610c2b32ba279f' 
  AND token = '5IxMpfBgmPBNMbZ9kr0bEvfO/oC73K3EcKA1IFPLrTI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}