SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '704df1a7cd6f6d03d12a974364820a090dac8f05b41914c2cc65df7fe9c79287' 
  AND token = 'iScgxa5ZjPM1dxQxDDTTpQpeJd0o9q4zsyIv+A6AT28=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00015

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}