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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8b9604a90012965481bd72939f2185ddd270e6a6e56fdfc9a21b146427a46d60' 
  AND token = 'zOlEqJOSJpWaIcg8UlmQuv7BDnQrbY9YrJEOphSFw7Q=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}