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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8c5151f5310e5de8daf8fb6cb6bc0a1c740dd128f8f5f0b774d43d65edeef906' 
  AND token = 'voA9TOwXPCm3BdJt89wpIv5SKzWXj3a34xtZZYWkxA8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00015

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}