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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5c24c13a87305256933d9214f4e20f00bf3b6cb602afeb7fa1690fb63fa646de' 
  AND token = 'meF79M2/vSWruhcIxm5gD+sHnVJ0SMJNpNg4Z+v08HQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}