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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '81122d87514c9f32d2cf11e644f57fbfcd1d09f612128ec352c619bc41632c3a' 
  AND token = '7z8M/qWwiBRFxS1Mlc6N240tySPxeKwj6TBuE2njBLY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00016

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}