SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0ae6d6c018aa6034af0d727c2f79bc6102f722d90889d68ba08e1f91642dd048' 
  AND token = 'kwoeYfbTQTbY3rr53l2rN4AS4oJ2xdfNy5+2OiZEFTA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}