SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'fd99b8c2e0d1abbaa1093a5c0721b8144a41aeb14d18e2db9a885498c75d41f9' 
  AND token = 'zYX+rFSb85P84uv+uhwmPIuFOabCZ8gnoAoHBd2nCLM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00039

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}