SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '66e4b46afa28641c3c76f30daf1f5e3389067820aa40c8c3640084b3815ab68f' 
  AND token = '6DzVTZQwYFtxAtQI+JFr0Rsa6wEzKDI777r+rJWuS3k=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00015

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}