SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '49480122414f8b4568125c607155e6bffd2bb07a997725b67fc295e8ab420f56' 
  AND token = 'Mk0fvS0YDIiZiuSJ3K9CpLDJo036mOzOjPb6dKevLqI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}