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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '457786e4f744e966d12d91dbece210a3ee3f468403766fc54fdc388085da67c4' 
  AND token = 'lhmlJoNl0h00kI9dfIDVa49bzgMwRAn5zdfV0wptaX4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}