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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e53ce05cdae3edb5c0f13c85dd3c99b76cce22bbad51462347460c7a19e93a8f' 
  AND token = 'AMTwZSAVbyBaY69f5yJIkUo+0McJlZYeIrRon2/1ZYE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}